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Pharmaceutical Care and Research: 2019; 19(1):59-62
DOI: 10.5428/pcar20190114
Retrospective analysis of pancreatitis induced by tigecycline
1. ZHOU Feng(Department of Pharmacy,Hainan Branch Hospital of Chinese PLA General Hospital, Hainan Sanya 572013,China
2. WU Xiaoyan(Department of Pharmacy,Hainan Branch Hospital of Chinese PLA General Hospital, Hainan Sanya 572013,China )
3. GUO Xiaohui(Department of Pharmacy,Hainan Branch Hospital of Chinese PLA General Hospital, Hainan Sanya 572013,China
ABSTRACT  Objective: To explore the regular pattern of the incidence of pancreatitis induced by tigecycline,so as to promote rational application of tigecycline clinically.Methods: Reports on adverse drug reactions of tigacycline both at home and abroad were collected and analyzed in the study.Results:A total of 13 independent literature reports were retrieved and reviewed.Most of the patients were male,and the majority of the patients were elderly people.Of the 13 cases,7 were treated with conventional dose of tigecycline.Pancreatitis caused by drugs all displayed symptoms of nausea and vomiting,accompanied by changes in serum indexes.After drug withdrawal and expectant treatment,most symptoms were relieved 2-15 days later.Conclusion:There is a clear correlation between tigecycline and pancreatitis.Serum indicators should be closely monitored in clinical practice,and special attention should be paid to those patients with cardiovascular and autoimmune diseases.
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ZHOU Feng,WU Xiaoyan,GUO Xiaohui,. Retrospective analysis of pancreatitis induced by tigecycline[J]. Pharmaceutical Care and Research / yao xue fu wu yu yan jiu. 2019; 19(1): 59-62.
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