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Pharmaceutical Care and Research: 2017; 17(5):352-355
DOI: 10.5428/pcar20170510
Case analysis of thrombocytopenia in a patient after percutaneous coronary intervention
1. HOU Wei1(1. Department of Pharmacy,Changhai Hospital,Second Military Medical University,Shanghai 200433,China
2. 2( 2. Department of Pharmacy,Tianjin Hospital,Tianjin 300211,China )
3. CAO AiLin1(1. Department of Pharmacy,Changhai Hospital,Second Military Medical University,Shanghai 200433,China )
4. QIAN Jiao1(1. Department of Pharmacy,Changhai Hospital,Second Military Medical University,Shanghai 200433,China
5. CHEN WenYao3(3. Department of Cardiovasology,Changhai Hospital,Second Military Medical University,Shanghai 200433,China )
6. NI Min4(4. Department of Pharmacy,Shanghai Tenth People’s Hospital,Shanghai 200072,China )
7. SHI Yan5( 5. Department of Pharmacy,Dongfang Hospital Affiliated to Tongji University,Shanghai 200120,China )
ABSTRACT  Objective: To analyze the causes of thrombocytopenia after percutaneous coronary intervention (PCI) in a patient with coronary heart disease. Methods: The causes of thrombocytopenia after PCI were analyzed based on the medical history and medication history. The suspected drugs were assessed according to the evaluation criteria of relevance formulated by National Center for Adverse Drug Reactions(ADRs) Monitoring,and Naranjo ADRs scoring criteria. Results: Through medical history and one by one drug screening,thrombocytopenia was suspected to be induced by antiplatelet drug ticagrelor. The platelet count gradually recovered following abandonment of the drug. Clopidogrel and aspirin were then used to continue dual antiplatelet therapy,and the patient’s condition improved and was duly discharged. Conclusion: The thrombocytopenia of the patient might be caused by ticagrelor.
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HOU Wei1,2,CAO AiLin1,QIAN Jiao1,CHEN WenYao3,NI Min4,SHI Yan5,. Case analysis of thrombocytopenia in a patient after percutaneous coronary intervention[J]. Pharmaceutical Care and Research / yao xue fu wu yu yan jiu. 2017; 17(5): 352-355.
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