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Abstract
Pharmaceutical Care and Research: 2017; 17(6):411-414
DOI: 10.5428/pcar20170604
Polyethylene imine and its coordination polymer gel used as gene vector
1. ZHANG Min1(1.Department of Biopharmacy,College of Food Science and Technology,Shanghai Ocean University,Shanghai 201306,China 13122223561@163.com)
2. WU JunWen1(1.Department of Biopharmacy,College of Food Science and Technology,Shanghai Ocean University,Shanghai 201306,China )
3. YAO Yun1(1.Department of Biopharmacy,College of Food Science and Technology,Shanghai Ocean University,Shanghai 201306,China )
4. YU Qian1(1.Department of Biopharmacy,College of Food Science and Technology,Shanghai Ocean University,Shanghai 201306,China )
5. GAO Shen2(2.Department of Pharmacy,Changhai Hospital,Second Military Medical University,Shanghai 200433,China )
6. LIU KeHai1(1.Department of Biopharmacy,College of Food Science and Technology,Shanghai Ocean University,Shanghai 201306,China khliu@shou.edu.cn)
ABSTRACT  Polyethylene imine (PEI) is a hot spot in the field of non-viral transgenic vector currently.Great progress has been made in the research on its cytotoxicity and targeting issues.A number of novel strategies,including structural transformation of PEI on targeting and biological degradability,metal ion coordination with PEI,particularly metal ion coordination with PEI to form a polymer gel,promise to have broad application prospects.
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Please cite this article as:
ZHANG Min1,WU JunWen1,YAO Yun1,YU Qian1,GAO Shen2,LIU KeHai1,. Polyethylene imine and its coordination polymer gel used as gene vector[J]. Pharmaceutical Care and Research / yao xue fu wu yu yan jiu. 2017; 17(6): 411-414.
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