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Abstract
Pharmaceutical Care and Research: 2018; 18(1):33-37
DOI: 10.5428/pcar20180109
Research advances in preparations of Tripterygium wilfordii for external use
1. GU YongWei1(1.Department of Pharmacy,Changhai Hospital,Second Military Medical University,Shanghai 200433,China 15628829972@163.com;)
2. 2(2.College of Pharmacy,Shandong University of Traditional Chinese Medicine,Jinan 250355,China 15628829972@163.com)
3. CHEN JinSong3(3.Department of Ultrasonography,Shanghai Xiangshan Traditional Chinese Medicine Hospital of Huangpu District,Shanghai 200020,China 18616590103@163.com)
4. YANG Meng1(1.Department of Pharmacy,Changhai Hospital,Second Military Medical University,Shanghai 200433,China )
5. YANG DiShun1(1.Department of Pharmacy,Changhai Hospital,Second Military Medical University,Shanghai 200433,China )
6. TANG XiaoMeng1(1.Department of Pharmacy,Changhai Hospital,Second Military Medical University,Shanghai 200433,China )
7. LIU JiYong1(1.Department of Pharmacy,Changhai Hospital,Second Military Medical University,Shanghai 200433,China liujiyong999@126.com)
ABSTRACT  Tripterygium wil fordii possesses various activities,including anti-inflammation,analgesia,antitumor and immunoregulation.However,the active substances are often toxic ingredients.For this reason,the research as how to decrease its toxicity and at the same time increase its efficacy has been an important research direction.As compared with the traditional route of oral medication,transdermal drug delivery has the advantages of less hepatotoxicity and absence of peak-valley drug concentration.Therefore,new route of Tripterygium wil fordii delivery has become an important hot spot in research.This paper made a comprehensive review from the perspectives of drug permeation-enhancing methods and related mechanisms involved in different drug permeation-enhancing techniques.At the same time,the paper also brought forth challenges and future direction in the research for Tripterygium wil fordii preparations for external use.
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Please cite this article as:
GU YongWei1,2,CHEN JinSong3,YANG Meng1,YANG DiShun1,TANG XiaoMeng1,LIU JiYong1,. Research advances in preparations of Tripterygium wilfordii for external use[J]. Pharmaceutical Care and Research / yao xue fu wu yu yan jiu. 2018; 18(1): 33-37.
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