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Abstract
Pharmaceutical Care and Research: 2018; 18(1):48-51
DOI: 10.5428/pcar20180112
Meta analysis of the effects of child Chiqiaoqingre granules plus Pudilan antiphlogistic oral liquid on hand-foot-and-mouth disease
1. GUO HongJu(Department of Pharmacy,No.306 Hospital of PLA,Beijing 100101,China )
2. SHI Ning(Department of Pharmacy,No.306 Hospital of PLA,Beijing 100101,China )
3. WANG Huan(Department of Pharmacy,No.306 Hospital of PLA,Beijing 100101,China )
4. GENG Shuai(Department of Pharmacy,No.306 Hospital of PLA,Beijing 100101,China )
5. ZHU YouZhi(Department of Pharmacy,No.306 Hospital of PLA,Beijing 100101,China )
6. CHANG LiRong(Department of Pharmacy,No.306 Hospital of PLA,Beijing 100101,China )
ABSTRACT  Objective: To evaluate the clinical efficacy of child Chiqiaoqingre granules (CCQG) plus Pudilan antiphlogistic oral liquid (PAOL) on hand-foot-and-mouth disease(HFMD).Methods: The randomized controlled trials (RCTs) for the treatment of HFMD with CCQG plus PAOL were retrieved from PubMed,China National Knowledge Infrastructure (CNKI),Database of China Biomedicine (CBM),VIP China Science and Technology Journal Database and Wanfang Data-Digitalization Journals.Retrieval time was from the inception of the databases to August 2016.Meta analyses were performed with RevMan 5.2 software.Results: Six papers involving 594 participants were ultimately included in the study.Meta-analysis results showed that the total effective rate in the treatment group was significantly different as compared with that of the control group,RR(95%CI) was 1.26 (1.14, 1.38)(P<0.000).There were also significant differences in body temperature recovery time,easing of sore throat and skin rash,as well as improvement time of ulcerative stomatitis (P<0.05) .But cure time did not show any statistical differences.Conclusion: Based on the present clinical evidence,the meta analysis results indicated that CCQG plus PAOL had definite clinical effects on HFMD.
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Please cite this article as:
GUO HongJu,SHI Ning,WANG Huan,GENG Shuai,ZHU YouZhi,CHANG LiRong,. Meta analysis of the effects of child Chiqiaoqingre granules plus Pudilan antiphlogistic oral liquid on hand-foot-and-mouth disease[J]. Pharmaceutical Care and Research / yao xue fu wu yu yan jiu. 2018; 18(1): 48-51.
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