Your Navigation:PCAR > Abstract
Search pcar
检索项:
检索词:
Abstract
Pharmaceutical Care and Research: 2018; 18(1):70-73
DOI: 10.5428/pcar20180118
Integrated pharmaceutical care for a case of severe adverse drug reactions induced by carbamazepine
1. WANG ShuoWen1(1.Department of Clinical Pharmacy,Shanghai People’s Hospital Affiliated to Shanghai Jiaotong University,Shanghai 200080,China wangshuowensy@163.com)
2. LEI You1(1.Department of Clinical Pharmacy,Shanghai People’s Hospital Affiliated to Shanghai Jiaotong University,Shanghai 200080,China )
3. 2(2.Faculty of Clinical Pharmacy,School of Pharmacy,Chongqing Medical University,Chongqing 400016,China )
4. SHI WeiFeng1(1.Department of Clinical Pharmacy,Shanghai People’s Hospital Affiliated to Shanghai Jiaotong University,Shanghai 200080,China )
5. LI Qin1(1.Department of Clinical Pharmacy,Shanghai People’s Hospital Affiliated to Shanghai Jiaotong University,Shanghai 200080,China )
6. FAN GuoRong1(1.Department of Clinical Pharmacy,Shanghai People’s Hospital Affiliated to Shanghai Jiaotong University,Shanghai 200080,China fanguorong@sjtu.edu.cn)
ABSTRACT  Objective: To investigate the role of clinical pharmacists in the pharmaceutical care of a case of severe adverse drug reactions (ADRs) induced by carbamazepine and the importance of pharmaceutical care in the prevention and treatment of ADRs.Methods: Careful analysis was made on the pharmaceutical care process of one patients with HLB-B*1502 gene mutation after administration of carbamazepine.Results: The pharmaceutical care advice and gene test results given by clinical pharmacists were accepted by clinical physicians and proved to beneficial to the development of individualized treatment profile.Conclusion: It was necessary for clinical pharmacists to be involved in integrated pharmaceutical care related with pharmacogenetic test of carbamazepine and monitoring of treatment drugs,so that drug safety could be ensured.
Welcome to PCAR! You are the number 466 reader of this article!
Please cite this article as:
WANG ShuoWen1,LEI You1,2,SHI WeiFeng1,LI Qin1,FAN GuoRong1,. Integrated pharmaceutical care for a case of severe adverse drug reactions induced by carbamazepine[J]. Pharmaceutical Care and Research / yao xue fu wu yu yan jiu. 2018; 18(1): 70-73.
References:
1. Ministry of Health of the People’s Republic of China.Standardized diagnosis and treatment of cancer pain(2011 ed)[J].Chin Clin Oncol,2012,17(2):153-158.In Chinese.
2. ZHU Xu,HE XiaoJing,ZHAO LiMei.Research progress in the pathogenesis of severe cutaneous adverse drug reactions induced by carbamazepine[J].Chin Pharm J,2012,47(18):1462-1464.In Chinese.
3. Friedmann P S,Strickland I,Pirmohamed M,et al.Investigation of mechanisms in toxic epidermal necrolysis induced by carbamazepine[J].Arch Dermatol,1994,130(5):598-604.
4. Hsiao Y H,Hui R C,Wu T,et al.Genotype-phenotype association between HLA and carbamazepine-induced hypersensitivity reactions:strength and clinical correlations[J].J Dermatol Sci,2014,73(2):101-109.
5. DAI Yan,WU YinHua,ZHU Ju’E,et al.Application of nystatin combined with glycerol in oral cavity fungal infection of patients with malignant cancer[J].Chin Foreign Health Abstract,2014,(22):142.In Chinese.
6. LIU YuCun,ZHANG HongYing,LIU LiPing,et al.Prevention of oral cavity fungal infection by nystatin with glycerol:a clinical observation [J].Chin J Nosocomiol,2004,14(6):646-647.In Chinese with English abstract.
7. Anon.Guiding principles of clinical applications of glucocorticoid drugs[J].Chin J Endocrinol Metabol,2012,28(2):Ⅰ0002-Ⅰ0033.In Chinese.
8. LIU Chu,TAN KaiMing,LI WeiQuan,et al.High-dose intravenous immunoglobulin combining with adrenal cortex hormone in treating serious drug eruption[J].Chin J Dermatovenereol,2004,18(6):343.In Chinese with English title.
9. PEI Li,LUO Yan,HUANG XianJin,et al.Risk and rational use of aprepitant[J].Chin J Drug Appl Monit,2015,12(5):310-312,318.In Chinese with English abstract.
10. Massaro A M,Lenz K L.Aprepitant:a novel antiemetic for chemotherapy-induced nausea and vomiting[J].Ann Pharmacother,2005,39(1):77-85.
11. Chen P,Lin J J,Lu C S,et al.Carbamazepine-induced toxic effects and HLA-B*1502 screening in Taiwan[J].N Engl J Med,2011,364(12):1126-1133.
12. CAO ZhiHao,LUO XiaoQun.Carbamazepine-induced drug eruption of epidermolysis bullosa associated with HLA-B*1502 allele in Han Chinese[J].Med Recap,2011,17(6):923-925.In Chinese with English abstract.
《药学服务与研究》杂志社 All Rights Reserved 网站备案号:鲁B2-20061008
·地址:上海市杨浦区长海路168号18号楼东三楼 邮政编码:200433
·联系电话(传真):86-21-65519829, 021-31162330
·电子邮件:PharmCR@vip.163.com
·技术支持:中国康网
管理员入口