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Pharmaceutical Care and Research: 2018; 18(2):81-86
DOI: 10.5428/pcar20180201
Research advances in nanoformulations of docetaxel
1. XU YouFa1(1.Teaching Office of Pharmaceutics,School of Pharmacy,Fujian University of Traditional Chinese Medicine,Fuzhou 350122,China
2. 2(2.Teaching Office of Pharmaceutics,School of Pharmacy,Second Military Medical University,Shanghai 200433,China
3. CHENG Dan2(2.Teaching Office of Pharmaceutics,School of Pharmacy,Second Military Medical University,Shanghai 200433,China )
4. FU ZhiQin1(1.Teaching Office of Pharmaceutics,School of Pharmacy,Fujian University of Traditional Chinese Medicine,Fuzhou 350122,China )
5. CHEN JianMing1(1.Teaching Office of Pharmaceutics,School of Pharmacy,Fujian University of Traditional Chinese Medicine,Fuzhou 350122,China
6. 2(2.Teaching Office of Pharmaceutics,School of Pharmacy,Second Military Medical University,Shanghai 200433,China
ABSTRACT  Docetaxel,one of the taxoid antitumor drugs,has good clinical effects on many kinds of cancer.However,due to the side effects caused by docetaxel itself and its solvent,its application is seriously restricted clinically.As nanoformulations have shown good perspective in terms of sustained drug release,prolonged drug efficacy,reduced toxicity and improved bioavailability of insoluble drugs,they are now a hot research topic both at home and abroad.This paper gives a comprehensive review on the current literature of nanoformulations of docetaxel as well as a perspective on future development and application,so as to provide reference for the research and development of new nanoformulations of docetaxel.
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XU YouFa1,2,CHENG Dan2,FU ZhiQin1,CHEN JianMing1,2,. Research advances in nanoformulations of docetaxel[J]. Pharmaceutical Care and Research / yao xue fu wu yu yan jiu. 2018; 18(2): 81-86.
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