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Abstract
Pharmaceutical Care and Research: 2018; 18(5):332-336
DOI: DOI:10.5428/pcar20180504
Analysis and intervention of potential drug risks in patients with multiple medications by clinical pharmacists
1. HU WenJuan1(1.Department of Pharmacy,People’s Hospital of Shanghai Pudong New District,Shanghai 201299,China huwenjuan2006@163.com)
2. 2(2.Department of Pharmacy,Shanghai Children’s Hospital,Children’s Hospital Affiliated to Shanghai Jiaotong University,Shanghai 200062,China huwenjuan2006@163.com)
3. HUANG Jin1(1.Department of Pharmacy,People’s Hospital of Shanghai Pudong New District,Shanghai 201299,China john70550@163.com)
4. 3(3.Department of Pharmacy,Yueyang Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai 200437,China john70550@163.com)
5. LI LuYi1(1.Department of Pharmacy,People’s Hospital of Shanghai Pudong New District,Shanghai 201299,China )
6. SUN HuaJun2(2.Department of Pharmacy,Shanghai Children’s Hospital,Children’s Hospital Affiliated to Shanghai Jiaotong University,Shanghai 200062,China )
ABSTRACT  Objective: To explore the role of clinical intervention by clinical pharmacists in potential risks of multiple medications. Methods: A total of 118 elderly patients with multiple medications of more than 5 drugs were enrolled for the study. The Beers criteria and the screening tool of old person potentially inappropriate prescriptions (STOPP) were used as the criteria for prescription screening and intervention. Drug application, disease distribution and drug category related with potential drug risks were analyzed in the process of the study. Then, interventions were made on the part of clinical pharmacists on potential drug risks by medication education at the time of discharge from hospital, as well as in outpatient pharmacist consultation and pharmacist ward round. Results: In the 118 patients, there were 50 (42.3%) patients with potential drug risks, 19 (16.10%) patients with disease-related potential drug risks and 31 (26.27%) patients with the risk of potential drug interactions, respectively. After pharmaceutical intervention, the categories and quantities of drugs, as well as the proportions of herbal drugs and health products all decreased considerably and medication adherence was also improved with statistical significance (P<0.05). Conclusion: Pharmaceutical intervention by clinical pharmacists in the patients with potential drug risks of multiple medications helps to improve rational application of drugs.
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Please cite this article as:
HU WenJuan1,2,HUANG Jin1,3,LI LuYi1,SUN HuaJun2,. Analysis and intervention of potential drug risks in patients with multiple medications by clinical pharmacists[J]. Pharmaceutical Care and Research / yao xue fu wu yu yan jiu. 2018; 18(5): 332-336.
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