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Pharmaceutical Care and Research: 2019; 19(1):5-9
DOI: 10.5428/pcar20190102
Development of the standards for specific prescription review of proton pump inhibitor and clinical improvement
1. XI Wenli1(1.Department of Pharmacy,Kaifeng Central Hospital,He’nan Kaifeng 475000,China
2. JIANG Wei2(2.Department of Neurology,Kaifeng Central Hospital,He’nan Kaifeng 475000,China )
3. XIE Yun1(1.Department of Pharmacy,Kaifeng Central Hospital,He’nan Kaifeng 475000,China )
ABSTRACT  Objective: To perform specific prescription review of proton pump inhibitor (PPI),so as to improve rational use of drugs clinically and provide solid evidence for standardized application of PPI.Methods: The standards for specific prescription review of PPI were developed through the approaches of the organization of specific prescription review team and information retrieval of related guidelines.Three hundred medical history records were randomly selected respectively from those patients with PPI who were hospitalized in Kaifeng Central Hospital from July to September 2016 and during the same time span of 2017,and then,the rationality of PPI was evaluated and analyzed systemically.Results:Of the 300 medical records selected from the records kept during the period of July to September 2016,there were 132 medical records with irrational medication (with an irrationality rate of 44%).The main problems involved included medication without indications (29.1%),irrational selection of dosage (16.5%) and irrational application and dosage (15.8%).Feedback of the review results was duly made to related administrative and clinical physicians.Through repeated communication and clinical propaganda,irrational medication of PPI was effectively brought under control.Specific prescription review made from July to September 2017 indicated that the number of irrational medication dropped to 36,with a sharp decrease of irrationality (a rate of only 12%).Conclusion:Through the development of the standards for specific prescription review of PPI,irrational application of such drugs as PPI could be effectively avoided and safe medication could be greatly assured for patients.
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XI Wenli1,JIANG Wei2,XIE Yun1,. Development of the standards for specific prescription review of proton pump inhibitor and clinical improvement[J]. Pharmaceutical Care and Research / yao xue fu wu yu yan jiu. 2019; 19(1): 5-9.
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