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Abstract
Pharmaceutical Care and Research: 2019; 19(2):111-113,142
DOI: 10.5428/pcar20190208
Multi-center clinical study of the efficacy of Aescuven forte tablets on complications during postoperative period after mixed hemorrhoidectomy
1. LU Hong1(1.Department of Anorectal Surgery,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200021,China my654-2@126.com)
2. ZHENG De1(1.Department of Anorectal Surgery,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200021,China )
3. ZHOU Hao2(2.Department of Anorectal Surgery,Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200030,China )
4. JIN Wei3(3.Department of Anorectal Surgery,Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200437,China )
5. JIN Wenqi4(4.Department of Anorectal Surgery,Shanghai Traditional Chinese Medical Hospital,Shanghai 200071,China )
6. HU Jie4(4.Department of Anorectal Surgery,Shanghai Traditional Chinese Medical Hospital,Shanghai 200071,China )
7. YING Guangyao5(5.Department of Anorectal Surgery,Shanghai Jiading Hospital of Traditional Chinese Medicine,Shanghai 201800,China )
8. TANG Xiaojun6(6.Department of Anorectal Surgery,Fangta Hospital of Traditional Chinese Medicine of Shanghai Songjiang District,Shanghai 201600,China )
9. YANG Wei1(1.Department of Anorectal Surgery,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200021,China 13917198396@163.com)
ABSTRACT  Objective: To observe the clinical efficacy of Aescuven forte tablets on complications during postoperative period after mixed hemorrhoidectomy. Methods: Two hundred and forty patients from 6 sub-centers were randomly divided into the trial group (n=120) and the control group (n=120),and all the patients underwent mixed hemorrhoidectomy. The patients began to take drugs on the first day after surgery (ie.d 1). The patients in the trial group were given oral administration of Aescuven forte tablets (2 tablets a time,bid),and the patients in the control group were given Zhining tablets (3 tablets a time,tid),all with a treatment course of 1 week. The main postoperative clinical symptoms of the 2 groups were closely observed,including the symptoms of anal edema,wound surface hemorrhage or pain. Then,the rate of symptom improvement was compared between the 2 groups. Results: On the d 1 (before drug administration),no significant differences regarding anal edema,wound surface hemorrhage or pain could be observed between the 2 groups (P>0.05). On day 3,anal edema (P<0.01) and wound surface pain (P<0.05) of the trial group were significantly superior to those of the control group. On day 7,anal edema,wound surface hemorrhage or pain in the trial group were also significantly superior to those of the control group,and statistical significance could be seen,when comparisons were made between them (P<0.01). The rate of treatment efficacy of the trial group was also significantly superior to that of the control group (87.50% vs 69.17%,P<0.05). Conclusion: Aescuven forte tablets could produce good therapeutic effects on anal edema,wound surface hemorrhage or pain after mixed hemorrhoidectomy,and they are significantly superior to those of Zhining tablets.
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Please cite this article as:
LU Hong1,ZHENG De1,ZHOU Hao2,JIN Wei3,JIN Wenqi4,HU Jie4,YING Guangyao5,TANG Xiaojun6,YANG Wei1,. Multi-center clinical study of the efficacy of Aescuven forte tablets on complications during postoperative period after mixed hemorrhoidectomy[J]. Pharmaceutical Care and Research / yao xue fu wu yu yan jiu. 2019; 19(2): 111-113,142.
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