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Pharmaceutical Care and Research: 2019; 19(2):114-117
DOI: 10.5428/pcar20190209
Clostridium difficile bacteremia:one case report and literature analysis
1. ZHENG Xiaoxiao1(1.Department of Pharmacy,Xuzhou First People’s Hospital,Jiangsu Xuzhou 221002,China
2. XU Shengqiu1(1.Department of Pharmacy,Xuzhou First People’s Hospital,Jiangsu Xuzhou 221002,China )
3. CHEN Erzhen2(2.Emergency Intensive Care Unit,Ruijin Hospital Affiliated to School of Medicine,Shanghai Jiaotong University,Shanghai 200025,China
4. HE Juan3(3.Department of Pharmacy,Ruijin Hospital Affiliated to School of Medicine,Shanghai Jiaotong University,Shanghai 200025,China
ABSTRACT  Objective: To provide solid evidence for optimized treatment of Clostridium difficile bacteremia (CDB) through analyzing successful treatment of one case of blood stream infection by C. difficile. Methods: Clinical manifestations,pathogenesis,risk factors and treatment regimens of one patient with CDB were analyzed,and the features of CDB were investigated based on related literature. Results: This rare case was a 68-year old male patient who had colitis accompanied with chronic perforation and suffered from infection by C. difficile. The patient recovered after anti-infective treatment with vancomycin and metronidazole. Conclusion: The incidence of CDB was relatively lower,but with high mortality. Early rational anti-infective treatment is of paramount importance in the treatment of the disease.
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ZHENG Xiaoxiao1,XU Shengqiu1,CHEN Erzhen2,HE Juan3,. Clostridium difficile bacteremia:one case report and literature analysis[J]. Pharmaceutical Care and Research / yao xue fu wu yu yan jiu. 2019; 19(2): 114-117.
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