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Abstract
Pharmaceutical Care and Research: 2019; 19(2):129-132
DOI: 10.5428/pcar20190213
Case analysis of individualized medication of voriconazole directed by therapeutic drug monitoring
1. ZHANG Hanjuan(Department of Pharmacy,Zhengzhou Seventh People’s Hospital of He’nan Province,Zhengzhou 450016,China zhanghj5605@163.com)
2. XIE Yuexu(Department of Pharmacy,Zhengzhou Seventh People’s Hospital of He’nan Province,Zhengzhou 450016,China )
3. REN Tong(Department of Pharmacy,Zhengzhou Seventh People’s Hospital of He’nan Province,Zhengzhou 450016,China )
4. CHEN Yongyan(Department of Pharmacy,Zhengzhou Seventh People’s Hospital of He’nan Province,Zhengzhou 450016,China )
ABSTRACT  Objective: To explore pharmaceutical care by clinical pharmacists in the individualized treatment with voriconazole,so as to provide reference for rational use of drugs. Methods: Through analysis of the treatment of 3 cases by voriconazole,the clinical thinking of clinical pharmacists involved in drug treatment was clearly elucidated,and the entry point of pharmaceutical care was analyzed. Results: Based on the results of therapeutic drug monitoring (TDM),clinical pharmacists proposed proper adjustment in the voriconazole treatment profile,and as a result,clinical efficacy was improved,the rate of adverse drug reactions (ADRs) was reduced,and more importantly medication safety was well ensured. Conclusion: TDM is a powerful tool for active involvement of clinical pharmacists in the individualized treatment with voriconazole,and its proper application could improve clinical efficacy and drug safety.
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Please cite this article as:
ZHANG Hanjuan,XIE Yuexu,REN Tong,CHEN Yongyan,. Case analysis of individualized medication of voriconazole directed by therapeutic drug monitoring[J]. Pharmaceutical Care and Research / yao xue fu wu yu yan jiu. 2019; 19(2): 129-132.
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